🎯 Key Discoveries
📊 Population Genetics Approach
- Multi-component ancestry analysis (64.3% Middle Eastern/Levantine)
- Ancient DNA database integration for population comparison
- Statistical validation through cross-validation methodology
- Comprehensive population structure analysis beyond regional categories
✅ Analytical Results
- Validated relationship to I16327.AG (Bronze/Iron Age Levant)
- Cross-validated K=10 optimal ancestral component model
- Multi-method convergence validation (ADMIXTURE + IBD + PCA)
- Comprehensive tri-continental ancestry profile
🧪 Technical Specifications
Cross-Validation Results: K=10 model optimal with CV error 0.51482
Dataset Composition: 143,495 high-quality SNPs across 61,816 samples
Ancient DNA Integration: AADR database with multi-method validation framework
🧬 Ancestral Components (K=10 Cross-Validated Model)
🔬 Component Analysis
Primary Pattern: The 64.3% Middle Eastern/Levantine component represents the dominant ancestral contribution, validated through population genetic analysis of Bronze/Iron Age samples.
Methodological Framework: K=10 model selected through cross-validation (CV=0.51482) using 143,495 high-quality SNPs across 61,816 samples, with multi-method validation including IBD and PCA convergence.
🏺 Ancient Population Analysis
📊 Population Genetic Analysis
Analysis identifies I16327.AG from Bronze/Iron Age Levant as the closest ancient population match (genetic distance: 0.0206). This relationship is validated through multi-method convergence including ADMIXTURE, IBD analysis, and PCA.
🧪 Validation Framework
Multi-Method Validation: ADMIXTURE genetic distances confirmed through IBD segment analysis and PCA convergence
Archaeological Context: Bronze/Iron Age Levantine populations representing regional genetic continuity
Statistical Confidence: Cross-validated through K=10 optimal model with CV error 0.51482
🔬 Analysis Overview
1. Data Preparation
Raw genomic data quality filtered and merged with 61,816 reference samples from curated databases
2. ADMIXTURE Analysis
Cross-validation testing across K-values, optimal K=10 selected with CV error 0.51482
3. Multi-Method Validation
Independent verification through IBD analysis and PCA convergence for statistical confidence
4. Ancient Population Analysis
Genetic distance calculations and archaeological context integration for population relationships
🧪 Technical Specifications
SNP Coverage: 143,495 high-quality autosomal markers
Reference Panel: AADR + Human Origins + SGDP + 1000 Genomes + curated populations
Cross-Validation: K=10 optimal model with CV error 0.51482
Validation Framework: Multi-method convergence (ADMIXTURE + IBD + PCA)
⚠️ Preliminary Archaic Analysis
Experimental: Initial hap-IBD analysis protocols suggest potential archaic human DNA signatures in Chr1-5 data. Results are preliminary and require extensive validation.
Note: Archaic DNA detection methods are experimental and not yet scientifically validated. All findings should be considered preliminary research only.